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China's BCI-Sonics Raises RMB200 Million to Build a Non-Invasive Brain-Computer Interface Using Ultrasound and AI

Shanghai-based BCI-Sonics has raised RMB200 million in a Pre-Series A round co-led by HSG and Yunqi Capital to develop a non-invasive brain-computer interface combining focused ultrasound, multimodal brain sensing and AI decoding.

By Nisha Omkumar · Author23 September 2026New
China's BCI-Sonics Raises RMB200 Million to Build a Non-Invasive Brain-Computer Interface Using Ultrasound and AI

BCI-Sonics, a Shanghai-based neurotechnology startup known in China as Huachao Shenkong, has raised RMB200 million (about $29.9 million) in a Pre-Series A round to develop a non-invasive brain-computer interface (BCI) that combines focused ultrasound, multimodal brain sensing and artificial intelligence.

The round, reported on 22 September 2026, was co-led by HSG, the firm formerly known as Sequoia China, and Yunqi Capital. Proxima Investment, Yuanhe Holdings, Xuhui Science and Technology Venture Capital and Deshi Investment also participated, while existing investors Matrix Partners China and Delian Capital increased their positions.

The financing brings the company's total funding since its founding in 2025 to nearly RMB300 million, a substantial sum for a company barely a year old.

A different route into the brain

Brain-computer interfaces aim to create a direct communication pathway between the brain and external devices. The most widely publicised efforts, including those of Neuralink, rely on implanting electrodes in or on the brain. Such invasive approaches can capture high-quality neural signals but require neurosurgery, which limits their use to patients with severe conditions and raises questions of long-term safety and cost.

BCI-Sonics is pursuing a non-invasive alternative built around three components. The first is focused-ultrasound neuromodulation, which uses precisely targeted sound waves to influence activity in specific brain regions without surgery. The second is multimodal brain-signal reading, which combines different external sensing methods to capture information about brain activity. The third is AI neural decoding, which interprets those signals.

Together, these components are intended to create a bidirectional system that can both "write" signals into the brain through ultrasound and "read" brain activity through external sensors, forming a closed loop.

The signal-quality challenge

The central difficulty for non-invasive BCIs is signal quality. The skull and surrounding tissues distort and weaken electrical signals from the brain, making them far harder to interpret than signals recorded directly from neurons. That is why invasive systems have historically achieved more precise control of external devices.

BCI-Sonics' thesis is that improved sensing hardware, the combination of multiple data sources and advances in AI decoding can close enough of that gap to make a useful closed-loop system possible. Machine learning models trained on large datasets can extract patterns from noisy signals that would be invisible to traditional analysis, and the use of ultrasound for stimulation offers a way to target deeper brain structures than many other non-invasive techniques.

It is an ambitious bet, and one that will require rigorous scientific validation.

Milestones and plans

The company says two generations of its focused-ultrasound BCI research products have completed development and safety reporting. It plans to move a closed-loop ultrasound BCI into clinical work in the first quarter of 2027. A consumer-oriented closed-loop product is also undergoing batch validation, and the company says it has established a strategic collaboration with a large international pharmaceutical company.

These are company-reported milestones rather than independent evidence of clinical effectiveness. Clinical studies will be needed to demonstrate that the system is safe and produces meaningful benefits for patients, and regulatory approval for medical applications will require extensive data.

Why investors are betting early

Investors are financing BCI-Sonics before clinical validation because the potential upside of non-invasive, bidirectional brain interfaces could be very large. Applications could span neuroscience research, treatments for central nervous system disorders, medical devices and, eventually, consumer products.

If brain-computer interfaces can work without surgery, the addressable market changes from a few thousand patients to potentially millions of people.
TIGI Analysis

Focused ultrasound has attracted growing scientific interest as a tool for studying and treating neurological and psychiatric conditions. Researchers have explored its potential for movement disorders, depression, addiction and chronic pain, among other conditions. A closed-loop system that can monitor brain activity and adjust stimulation in response could, in principle, deliver more personalised and effective therapies.

The involvement of a large international pharmaceutical partner hints at another possible application: using brain monitoring and stimulation alongside drug development, for example to measure how therapies affect brain function or to identify patients most likely to respond.

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China's growing neurotechnology ambitions

The round reflects China's growing ambitions in neurotechnology. Chinese authorities have identified brain-computer interfaces as a priority future industry, and a growing number of Chinese startups are pursuing both invasive and non-invasive approaches. Major venture firms, including HSG, have become more active in deep-tech sectors as consumer internet investment opportunities have become less attractive.

Global competition in the field is intensifying. In the United States, companies such as Neuralink and Synchron have advanced implanted devices into human trials, while other firms pursue non-invasive or minimally invasive approaches. Research institutions and startups in Europe are also active. The race is not only commercial but strategic, as governments view neurotechnology as a frontier with implications for healthcare, defence and computing.

Ethical and regulatory questions

Brain-computer interfaces raise profound ethical questions. Technologies that can read or influence brain activity touch on privacy, consent, autonomy and the potential for misuse. Consumer applications in particular will face scrutiny about how neural data is collected, stored and used. Several jurisdictions have begun to debate specific protections for so-called neural data.

For BCI-Sonics, navigating these issues responsibly will be important for public trust and regulatory acceptance, particularly as it pursues consumer products alongside clinical applications.

The consumer question

The company's parallel work on a consumer-oriented closed-loop product sets it apart from many medical BCI developers. Consumer neurotechnology, including headbands that monitor brain activity for meditation, sleep or focus, has existed for years, but most products have relied on relatively simple sensing and have made modest claims. A consumer device that incorporates ultrasound stimulation would represent a significant step, and would likely face scrutiny from regulators about safety, efficacy claims and the boundary between wellness and medical use.

For investors, a consumer line could offer earlier revenue than clinical products, which require lengthy trials and approvals. But it also brings reputational risk: overpromising in consumer markets could undermine the credibility of the company's clinical ambitions.

The road ahead

BCI-Sonics has assembled significant capital and a prominent investor base in a remarkably short time. Its next milestones, including the start of clinical work in early 2027, will begin to show whether its non-invasive approach can deliver on its promise.

If the company can demonstrate reliable, clinically meaningful results without surgery, it could help redefine the brain-computer interface field and open the technology to far larger patient populations. If not, it will join a long list of neurotechnology ventures that found the brain more complex than anticipated. Either way, the round underscores how rapidly investment in neurotechnology is accelerating, and how central AI has become to efforts to understand and interact with the human brain.

TagsBCI-SonicsBrain-Computer InterfaceNeurotechnologyFocused UltrasoundAIHSGYunqi CapitalChinaMedTechNeuroscienceDeep TechPre-Series A

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